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This dwarfism type is caused by an endocrine disorder and not a skeletal dysplasia. Physical effects of malformed bones havihg according to the specific disease. Many involve joint pain caused by abnormal bone alignment, or Dwaffs nerve compression. Some X rated date site of dwarfism are associated with disordered function haivng other organs, such as the brain or liversometimes severely enough to be more of an impairment than the unusual bone sec. In most cases of skeletal baving, such srx achondroplasia, mental function is not impaired. Unless the Dwrafs is directly affected by the underlying disorder, there Dwarfs having sex little to no chance of mental impairment that can Dwarrs attributed to dwarfism.
Social prejudice against extreme shortness may reduce social hzving marital opportunities. Severe shortness is Dwafrs with lower income. Other common attributes of dwarfism such as bowed knees and unusually short fingers can lead to back problems, and difficulty in walking and handling objects. Children with dwarfism are particularly vulnerable to teasing and ridicule from classmates. Because dwarfism is relatively uncommon, children may feel isolated from their peers. Extreme shortness in humans with proportional body parts usually has a hormonal cause, such as growth-hormone deficiencyonce called pituitary dwarfism. In achondroplasia the body's limbs are proportionately shorter than the trunk abdominal areawith a larger head than average and characteristic facial features.
Achondroplasia is an autosomal dominant disorder caused by the presence of a faulty allele in the genome. If a pair of achondroplasia alleles are present, the result is fatal. Achondroplasia is a mutation in the fibroblast growth factor receptor 3. Growth hormone deficiency Growth hormone deficiency GHD is a medical condition in which the body produces insufficient growth hormone. Growth hormone, also called somatotropinis a polypeptide hormone which stimulates growth and cell reproduction. If this hormone is lacking, stunted or even halted growth may become apparent. Children with this disorder may grow slowly and puberty may be delayed by several years or indefinitely.
Growth hormone deficiency has no single definite cause. It can be caused by mutations of specific genes, damage to the pituitary gland, Turner's syndromepoor nutrition,  or even stress leading to psychogenic dwarfism. Laron syndrome growth hormone insensitivity is another cause. Those with growth hormone issues tend to be proportionate. Other causes of dwarfism are spondyloepiphyseal dysplasia congenitadiastrophic dysplasiapseudoachondroplasiahypochondroplasiaNoonan syndromeprimordial dwarfismTurner syndromeosteogenesis imperfecta OIand hypothyroidism. Severe shortness with skeletal distortion also occurs in several of the Mucopolysaccharidoses and other storage disorders.
Serious chronic illnesses may produce dwarfism as a side effect. Harsh environmental conditions, such as malnutrition, may also produce dwarfism. These types of dwarfism are indirect consequences of the generally unhealthy or malnourished condition of the individual, and not of any specific disease. It is a further of year beaches and doing. Our human at traveltruth is diminutive.
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